Monthly Archives: July 2016

How Clay Siegall Has Helped in Shaping Seattle Genetics

Dr Siegall serves as the President, CEO and the Chairman of the board of Seattle Genetics, Inc. He acquired his B.S in Zoology from Maryland University and a Genetics PhD from George Washington University. He also cofounded Seattle Genetics back then in 1998 after working for Bristol Myers Squibb Pharmaceutical Research Institute for 6 years. Dr. Siegall also built the company with a strong emphasis on cancer therapies. The company is established on a foundation of rigorous research, drug development processes and scientific innovation.

Dr. Siegall’s Achievements

Seattle Genetics has gained critical acclaim due to its antibody drug conjugate (ADC) platform. The platform targets diverse autoimmune and cancer indications. Under Dr. Siegall’s management, the company has acquired several strategic licenses mainly for its ADC technology. These include AbbVie, GlaxoSmithKline, Pfizer and Genentech (Roche). These licenses have accumulated over 300 million dollars to date. As a sign of progress, there are over 20 ADCs in the clinical sector using the company’s technology. Dr. Siegall’s capital raising ideas have enabled Seattle Genetics to secure more than 675 million dollars through private and public funding.

Dr. Siegall was a keynote speaker at the CHI’s 5th Annual Antibody Drug Conjugates Conference held in Boston. In his speech, he talked about how ADCETRIS (brentuximab vedotin) is being used to treat over 15,000 lymphoma patients globally. He also mentioned that Seattle Genetics has collaborated with several leading pharmaceutical and biotechnology companies.

His Perspectives Regarding ADC Technology

Dr. Siegall highlighted that his company is leveraging the experience gathered from ADC and driving innovation into ADC technology. He also mentioned that two pipeline programs have launched in addition to the ADCETRIS product. These include SGN-CD19A and SGN-CD33A. SGN-CD33A was developed to provide treatment to acute leukemia cells. On the other hand SGN-CD19A is an antibody drug conjugate that targets CD19 that is a protein found in B-cell malignancies.

Information on the technologies that are used in both pipeline programs was presented to the American Association for Cancer Research (AACR) Annual meeting in April 2015. This information focused on the new linker, antibody, cytotoxic payload components and drug designs for the pipeline programs.

Learn more:

http://www.xconomy.com/author/csiegall/

https://www.crunchbase.com/person/clay-b-siegall#/entity

Adam Goldberg Is Setting Pace With JustFab

Entrepreneur Adam Goldberg has set out to shape fashion e-commerce. The co-founder and co-CEO of JustFab has a talent for spotting the hottest trends and expanding businesses and adding levity to a career that many take way too seriously.

Adam Goldenberg has always been a business-minded person. He launched his own company as a teen and sold it three years later to MySpace owner Intermix Media. He made a bundle, but didn’t stop there. Adam gained so much success in such a short period of time that he quit high school and joined Intermix in the capacity of Strategic Planning President.

Don’s incredible business savvy helped him make a stack of money for a lot of people — himself included. He was a millionaire by the time he reached 20.

Adam founded JustFab in 2006 then Shoe Dazzle a few years later. An e-commerce innovator, he launched a succession of health and beauty platforms that are cutting edge and conceptually innovative. Not only did Adam want to create something affordable, he wanted to tap into social media to increase sales.

After creating a social internet platform, he was able to do what many before him failed to. Adam Goldenberg hired a slew of designers and consultants to keep him on the right track. He created the online e-commerce monthly auto-ship platform. For instance, Shoe Dazzle charges a membership fee of $39.99 per month. to try out a wide selection of shoes, handbags and other accessories.

Adam says it’s not just about shipping thing out, it’s about making it fun and exciting. “We change up items, offer monthly deals and do things to keep the site fresh.” He must be doing something right because Shoe Dazzle is one of the fastest growing e-companies in the U.S. See: http://vator.tv/person/adam-goldenberg

There are a lot of business people attempting to duplicate his platform. Kimora Lee Simmons, founder of Baby Phat, took Adam’s advice. “I’ve known Kimora for a long time. She has a great eye for fashion and we learn a lot from each other.”

Adam Goldenberg has built JustFab into a multi million dollar company. He says that billionaire status is right around the corner.

Kyle Bass Sees Negative Economic Futures

China has built an economic system based on a growth bubble in a way very similar to America’s own proceedings prior the 2008 financial meltdown. It’s not a one-to-one comparison, but the similarities are there; namely: providing financial reach to those with no ability to reimburse their spendings. Kyle Bass believes that this expanding credit bubble will result in an economic implosion. He doesn’t think it’ll be like what was seen in America during the 2008 financial meltdown. Bass has said he doesn’t see a “Lehman Brothers Moment” in China’s future. He does, however, predict that there’s a forty to fifty percent chance an economic downturn in China will affect the United States economy by the end of 2016. He says the collapse must come in the next two to three years.

All that sounds like qualitative analysis, till one realizes that a fifty percent chance is basically binary: either or, a flip of the coin. A forty percent chance is even less likely. Or look at it this way: there’s a fifty to sixty percent chance there won’t be an economic downturn based on China’s economy by the end of 2016. Kyle Bass has basically said a non-thing any person with even a passing familiarity with economics could say. Every year there’s technically a fifty percent chance of economic downturn in any country; it just depends on the factors involved in economic development that year. Consider the Fukushima nuclear meltdown in Japan–that certainly wasn’t planned.

But Kyle Bass is no stranger to market manipulation, as this must be; else he demonstrates a level of incompetence. Bass started CAD, the Coalition for Affordable Drugs. CAD uses politics to decimate pharmaceutical prices facilitating stock declination and allowing Bass to short-sell his holdings for millions in profit. He legally manipulates the stock market and gets away with it.

Bass is also closely tied to Cristina Fernandez de Kirchner. De Kirchner is known worldwide for defaulting Argentina’s economy twice in only thirteen years. Yet Bass continuously praises her financial endeavors. His own Argentinian heritage is no excuse; if anything that makes it more perplexing he would praise a leader destroying his country.

With these things in mind, when Bass makes a market prediction, consider the possibility he’s playing an angle.

Wen by Chaz Dean: Its Effect on Em’s Fine Hair

Many questions begin to flow through your mind before deciding to switch your beauty regiment up a bit–especially when dealing with your precious hair. Investing in quality products should alleviate any stressful concerns, but that does not determine just what those products would do to your own hair. Well, certain customers decide to put wandering minds to rest by conducting their own experiments and reporting their results. Emily McClure decided to put any rumors pertaining to WEN hair by Chaz Dean products to rest by using a cleansing conditioner on her fine hair for a week. The results were no surprise, of course! Read, http://www.wen.com/before-after.html.

Wen hair products were created by celebrity hair stylist, Chaz Dean. The humble personality decided that it was time to craft products for both celebrities and the average person that would leave all hair types the healthiest that they can be. And sell them on the Sephora beauty market. As the products clear plenty of shelf space by eliminating the need for countless, potentially harmful chemicals, the beauty industry can breathe a sigh of relief each day. So, what happened with Emily?

Again, her results were no surprise–her hair turned out perfect! Her routine washes transformed her fine hair to voluminous locks, added a shine that most cannot believe came out of a bottle, and made her hair generally healthier.Wen hair is available online, from sites like Amazon and eBay.

Read the Guthy Renker product review here: http://www.guthy-renker.com/products/beauty/wen-haircare/

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