How Clay Siegall Has Helped in Shaping Seattle Genetics

Dr Siegall serves as the President, CEO and the Chairman of the board of Seattle Genetics, Inc. He acquired his B.S in Zoology from Maryland University and a Genetics PhD from George Washington University. He also cofounded Seattle Genetics back then in 1998 after working for Bristol Myers Squibb Pharmaceutical Research Institute for 6 years. Dr. Siegall also built the company with a strong emphasis on cancer therapies. The company is established on a foundation of rigorous research, drug development processes and scientific innovation.

Dr. Siegall’s Achievements

Seattle Genetics has gained critical acclaim due to its antibody drug conjugate (ADC) platform. The platform targets diverse autoimmune and cancer indications. Under Dr. Siegall’s management, the company has acquired several strategic licenses mainly for its ADC technology. These include AbbVie, GlaxoSmithKline, Pfizer and Genentech (Roche). These licenses have accumulated over 300 million dollars to date. As a sign of progress, there are over 20 ADCs in the clinical sector using the company’s technology. Dr. Siegall’s capital raising ideas have enabled Seattle Genetics to secure more than 675 million dollars through private and public funding.

Dr. Siegall was a keynote speaker at the CHI’s 5th Annual Antibody Drug Conjugates Conference held in Boston. In his speech, he talked about how ADCETRIS (brentuximab vedotin) is being used to treat over 15,000 lymphoma patients globally. He also mentioned that Seattle Genetics has collaborated with several leading pharmaceutical and biotechnology companies.

His Perspectives Regarding ADC Technology

Dr. Siegall highlighted that his company is leveraging the experience gathered from ADC and driving innovation into ADC technology. He also mentioned that two pipeline programs have launched in addition to the ADCETRIS product. These include SGN-CD19A and SGN-CD33A. SGN-CD33A was developed to provide treatment to acute leukemia cells. On the other hand SGN-CD19A is an antibody drug conjugate that targets CD19 that is a protein found in B-cell malignancies.

Information on the technologies that are used in both pipeline programs was presented to the American Association for Cancer Research (AACR) Annual meeting in April 2015. This information focused on the new linker, antibody, cytotoxic payload components and drug designs for the pipeline programs.

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Adam Goldberg Is Setting Pace With JustFab

Entrepreneur Adam Goldberg has set out to shape fashion e-commerce. The co-founder and co-CEO of JustFab has a talent for spotting the hottest trends and expanding businesses and adding levity to a career that many take way too seriously.

Adam Goldenberg has always been a business-minded person. He launched his own company as a teen and sold it three years later to MySpace owner Intermix Media. He made a bundle, but didn’t stop there. Adam gained so much success in such a short period of time that he quit high school and joined Intermix in the capacity of Strategic Planning President.

Don’s incredible business savvy helped him make a stack of money for a lot of people — himself included. He was a millionaire by the time he reached 20.

Adam founded JustFab in 2006 then Shoe Dazzle a few years later. An e-commerce innovator, he launched a succession of health and beauty platforms that are cutting edge and conceptually innovative. Not only did Adam want to create something affordable, he wanted to tap into social media to increase sales.

After creating a social internet platform, he was able to do what many before him failed to. Adam Goldenberg hired a slew of designers and consultants to keep him on the right track. He created the online e-commerce monthly auto-ship platform. For instance, Shoe Dazzle charges a membership fee of $39.99 per month. to try out a wide selection of shoes, handbags and other accessories.

Adam says it’s not just about shipping thing out, it’s about making it fun and exciting. “We change up items, offer monthly deals and do things to keep the site fresh.” He must be doing something right because Shoe Dazzle is one of the fastest growing e-companies in the U.S. See:

There are a lot of business people attempting to duplicate his platform. Kimora Lee Simmons, founder of Baby Phat, took Adam’s advice. “I’ve known Kimora for a long time. She has a great eye for fashion and we learn a lot from each other.”

Adam Goldenberg has built JustFab into a multi million dollar company. He says that billionaire status is right around the corner.

Kyle Bass Sees Negative Economic Futures

China has built an economic system based on a growth bubble in a way very similar to America’s own proceedings prior the 2008 financial meltdown. It’s not a one-to-one comparison, but the similarities are there; namely: providing financial reach to those with no ability to reimburse their spendings. Kyle Bass believes that this expanding credit bubble will result in an economic implosion. He doesn’t think it’ll be like what was seen in America during the 2008 financial meltdown. Bass has said he doesn’t see a “Lehman Brothers Moment” in China’s future. He does, however, predict that there’s a forty to fifty percent chance an economic downturn in China will affect the United States economy by the end of 2016. He says the collapse must come in the next two to three years.

All that sounds like qualitative analysis, till one realizes that a fifty percent chance is basically binary: either or, a flip of the coin. A forty percent chance is even less likely. Or look at it this way: there’s a fifty to sixty percent chance there won’t be an economic downturn based on China’s economy by the end of 2016. Kyle Bass has basically said a non-thing any person with even a passing familiarity with economics could say. Every year there’s technically a fifty percent chance of economic downturn in any country; it just depends on the factors involved in economic development that year. Consider the Fukushima nuclear meltdown in Japan–that certainly wasn’t planned.

But Kyle Bass is no stranger to market manipulation, as this must be; else he demonstrates a level of incompetence. Bass started CAD, the Coalition for Affordable Drugs. CAD uses politics to decimate pharmaceutical prices facilitating stock declination and allowing Bass to short-sell his holdings for millions in profit. He legally manipulates the stock market and gets away with it.

Bass is also closely tied to Cristina Fernandez de Kirchner. De Kirchner is known worldwide for defaulting Argentina’s economy twice in only thirteen years. Yet Bass continuously praises her financial endeavors. His own Argentinian heritage is no excuse; if anything that makes it more perplexing he would praise a leader destroying his country.

With these things in mind, when Bass makes a market prediction, consider the possibility he’s playing an angle.

Wen by Chaz Dean: Its Effect on Em’s Fine Hair

Many questions begin to flow through your mind before deciding to switch your beauty regiment up a bit–especially when dealing with your precious hair. Investing in quality products should alleviate any stressful concerns, but that does not determine just what those products would do to your own hair. Well, certain customers decide to put wandering minds to rest by conducting their own experiments and reporting their results. Emily McClure decided to put any rumors pertaining to WEN hair by Chaz Dean products to rest by using a cleansing conditioner on her fine hair for a week. The results were no surprise, of course! Read,

Wen hair products were created by celebrity hair stylist, Chaz Dean. The humble personality decided that it was time to craft products for both celebrities and the average person that would leave all hair types the healthiest that they can be. And sell them on the Sephora beauty market. As the products clear plenty of shelf space by eliminating the need for countless, potentially harmful chemicals, the beauty industry can breathe a sigh of relief each day. So, what happened with Emily?

Again, her results were no surprise–her hair turned out perfect! Her routine washes transformed her fine hair to voluminous locks, added a shine that most cannot believe came out of a bottle, and made her hair generally healthier.Wen hair is available online, from sites like Amazon.


Desiree Perez Is The Fire Behind Roc Nation’s Tidal


Tidal has went through quite a lot lately. They have successfully completed a few huge album exclusives in a row from their co owner Rihanna, T.I, Beyonce, and Kanye West. The Tidal rose to a very high point, actually being the highest point ever in the Itunes store which was following Kanye West’s TLOP drop and his exclusive. It is still in progress. It has been reported that a million trial members have been added since February 22nd.

However, after the defection of quite a few executives, (Tidal has it’s 3rd CEO, which is the former SoundCloud Chief Business executive officer Jeff Toig who joined in late 2015),it is questionable of who exactly is orchestrating these five-start executive artist plays. There have been sources that are behind the scene saying that it is a lady named Desiree Perez. Jay Z and her are close associates and they have been for a very long time. She runs SC Enterprises along with her husband, Juan Perez.

Desiree Perez is apparently is a very fierce and touch negotiator and a numbers cruncher. It was also said that she has a history and a street rep that even Empire’s Cookie wouldn’t dare try to challenge. The N.Y. Daily News calls her “Babe Ruthless”. Desiree Perez is known for being a boss. Desire Perez negotiated Beyonce’s Formation stadium tour and she also had a strong hand in Rihanna’s samsung deal.

The Hova Circle of Influence is made up of Desiree Perez, Jay Z, Chaka Pilgrim, Jana Fleischman, and Jay Brown. They are big bosses running Roc Nation, and many other parts of management, labeling, publishing, and even the operation of Tidal itself. So basically, Perez and her crew run the entire operation.

This streaming service has been building its own lane and is geared towards the young consumers. They have to make an impression when it comes to other other rivals like Spotify and Apple Music. Tidal is focused on what is next and what’s new instead of a catalog which will end up costing more.

However, Tidal will cost more than it’s competition. It is based on two subscription tiers. It will not be free but it does offer a free two week trial to test it out. However, it seems pretty affordable at just $9.99 a month. When listeners get the premium tier, they will have access to high definition music videos.

Duda Melzer And His Grand Accomplishments


Duda Melzer is the president and the chairman of Grupo RBS. Duda Melzer’s full name is Eduardo Sirotsky Melzer, and he also serves as chairman for Grupo RBS. Apart from being chairman of Grupo RBS, Duda Melzer is the founder of eBricks Digital. EBricks Digital is an investment company that focuses on the digital industry. EBricks Digital is a company that operates in North and South America. Duda Melzer is a regular guest and participant in conferences that are held by Google and Sun Valley. Duda Melzer is an individual that went to college for a business administration degree; he also earned his MBA at Harvard. Duda Melzer is fluent in Portuguese, Spanish, and English. Duda Melzer began his career in the United States, and later he was able to serve as a financial analyst at the media company called BoxTop media.

In 2015, Duda Melzer became one of the leaders at The Cambridge Institute For Family Enterprise. The Cambridge Institute For Family Enterprise works with different generations of families all around the world. This Institute works with these individuals that have leading roles in their family’s Enterprises, and it helps them to make their business grow and flourish. Duda Melzer was vice president of marketing and business development in Grupo RBS; he was Senior financial analyst at Delfi in the United States, and he was a consult at Booz Allen Hamilton. Duda Melzer was also named the entrepreneur of the year in 2005 by Ernst and Young.

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How California’s Drought Affects Ski Resorts with KCRW

California’s drought, a topic that has been in the public eye for a while now, was deemed a State of Emergency in January of 2015. Lack of precipitation in the region has caused massive water loss for many inhabitants, including ski resorts residing in the northern part of the state that thrives off of the winter snowfall.

I was able to tune into KCRW where Madeline Brand was fortunate enough to interview the CEO of Squaw Valley Ski Holdings, Andy Wirth. Madeline mentions how many resorts are debating changing their business models, having prematurely ended skiing seasons due to the issue. Learn more about Andy Wirth:

She goes on to say that experts predict, if the drought persists, within 20-years there will be no skiing in California. Andy quells her concern for his resort, assuring our hostess that the resort has taken every precaution to keep business booming. Andy does agree that the lack of snow has staggard business to the resort, but only slightly.

He states that out of the 6000 acres of mountain, 4000 acres is still operational; that’s plenty to keep the lift doors open. Subsequently, he says that the resort is acclimating to the challenge, not only by creating more snow but also hedging both summer and winter months. With this approach, the resort can take advantage of events that take place during the summer, including weddings, meetings, and the IronMan triathlon of which Andy Wirth is a huge supporter.

During a skydiving run, Andy Wirth was unfortunate enough to land in a vineyard, causing him to completely sever his right arm. During his recovery, he unexpectedly befriended a group of navy seals that happened to be training in Squaw Valley. For Andy, that incident was a blessing in disguise as he states,”quite a few of them have become good friends and their spirit, counsel and narrative has truly been an important part of my recovery.”

He has gone so far as to set up a fundraiser for the purpose of honoring those who give their lives for the stability and freedom of this country. To date, he has raised $14,460. Learn more about Andy Wirth:

Andy Wirth has shown time and time again, from working his way up to CEO of the resort to his tragic accident, that he is extremely resourceful in what some made deem a “dire situation. He harnesses this tanasity with his ability to pull through situations stronger than ever assuring us that December and January are quite favorable for his resorts, dispite the lack of snowfall.

Is Oil Responsible for Venezuela’s Crisis?

For a little over a century, Venezuela has been exporting its oil. Since 1914, this oil has been a large component of the government’s economy. Although it is still the country with the most untouched oil in the world, Venezuela is in a terrible economic situation at this present time. In a recent article, oil is blamed for the state of the country. Part of the crisis is due to the low prices on oil barrels exported from Venezuela. Because they are earning less for the oil, which is the chief export, the government does not have enough money to buy necessary materials to import for their people. This has caused scarcities for food, toiletries, energy and even work, reveals insider David Osio.

Poor care of oil fields, which are some of the world’s oldest, has also caused other damage to Venezuela’s ecosystem. The production areas were not maintained properly, and many are all but abandoned at this time. The waters are plagued with oil, which leaked from ruptured pipes used for oil extraction, and this has affected the fishing. According to El Venezolano, local fishermen catch more oil than fish in their nets in Venezuelan waters, which has caused much hardship as they can not provide for their families either.


The Midas Legacy’s Excellent Counseling Services

The Midas Legacy is an advisory firm that majorly focusses on guiding its clients on how to be successful and wealth management. Based in Winter Garden, Florida, the company serves a wide assortment of customers who include investors, growing entrepreneurs, individuals who are looking for internal peace and happiness, people who want to be healed with natural medicine, and anyone who wants to change his or her financial state positively. The firm and its employees are committed to ensuring that its mission of making people successful is achieved. The Midas Legacy offers resources to members who have the proficiency of positively revolutionizing the entrepreneurship, retirement, natural health and the real estate sectors.

The mission of making the members prosperous starts from the time they pursue the company’s advisory services. A counseling book referred to as The Midas Code is given to clients as soon as they join as members of The Midas Legacy. The members are advised on various ventures by the firm’s professionals who are highly skilled in book writing, stock markets, entrepreneurship and other careers. The experts of the company aim at a common goal of satisfying the client’s specific needs.

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Real Estate Riches

Wall Street Informer

The head experts who serve The Midas Legacy are Sean Bower, Mark Edward, and Jim Samson. Sean Brower is high skilled in business journalism and has outstanding knowledge of finance and markets. He works at the company as advisor of capital markets and business decision making. Mr. Bower’s works have been cited many times in international magazines such as the International Business Times and the Japan’s Nikkei. Mark Edward has excellent skills in natural medicine and serves as the company’s advisor to clients who require natural healing services. Jim Samson is professional in stock trading, entrepreneurship, and book writing. Mr. Samson has written many books, which have been best-sellers and he has an exceptional experience in real estate since he has been in the industry for close to twenty years.

The Midas Legacy is a philanthropic organization and has participated in many charity activities. The company makes contributions to the Florida Sheriffs Association and has been appreciated by the institution as a Gold Business Member. Midas is also a benefactor of the St. Jude Children’s Research Hospital and the Central Florida-based Give Hope Foundation, which both help in dealing with childhood cancer and other detrimental conditions. The American Society for Prevention of Cruelty to Animals, the Salvation Army, and the Wounded Warrior Projects also receive support from the company’s charity contributions.

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Brad Reifler Understands the Investment Needs of the Ninety-Nine Percent

Founder and CEO of Forefront Capital, Brad Reifler, saw a need in the world of investments, and he filled it. Although, he himself is in the top one percent, he understands the investing needs of the ninety-nine percent, and is happy to share with them his understanding of the market. After retiring, Reifler’s father-in-law entrusted his life savings to Reifler which enabled Reifler to see firsthand the limited investment options that his father-in-law, and others like him, had. It was then that Reifler realized that the ninety-nine percent needed opportunity, help, and guidance in order to participate in the market. And, what is Reifler’s advice to the ninety-nine percent?

Reifler recommends that an investor should not invest all of his or her money in the market. In addition, Reifler believes it is important for investors to get to know who the people are that they have allowed to invest their hard-earned money. Finally, a person should have investment goals, and he or she should keep track as to how their investments are meeting those goals.

However, even Reifler understands that the financial market is not always precise. He himself invested money in a college savings plan for his daughters and ended up losing on the deal. However, overall he has had an extremely successful financial career. He has a degree in Economics and Political Science from Bowdoin College. After graduating, he went on to focus on global derivatives and in 1982 founded Reifler Trading Corporation. Since that time, he has enjoyed continued success in the financial sector and helped in the creation of several more companies.  Be sure to follow Brad on Twitter @BradleyR.